CEFTILOX-MX Tab
Composition: Moxifloxacin Hydrochloride I.P.equivalent. to Moxifloxacin 400 mg Cefixime (As Trihydrate) I.P.equivalent. to Anhydrous Cefixime 400 mg Excipients q.s.
Indication: for the treatment of bacterial infections, including respiratory tract infections, urinary tract infections, and skin infections. The combination is effective against a broad range of bacteria and is used when dual therapy is needed to enhance antibacterial coverage.
Packing: 10 x 10
Pack Type: Tab

Description

CEFTILOX-MX Tablet: Comprehensive Overview

Introduction CEFTILOX-MX Tablet is a powerful antibiotic formulation that combines Moxifloxacin 400 mg & Cefixime 400 mg, offering a broad-spectrum antibacterial action against various bacterial infections. This combination is particularly effective in treating respiratory tract infections, urinary tract infections, and other bacterial infections that require potent antibiotic therapy.

Composition

  • Moxifloxacin 400 mg
  • Cefixime 400 mg

Mechanism of Action

  • Moxifloxacin 400 mg: A fourth-generation fluoroquinolone, Moxifloxacin 400 mg works by inhibiting bacterial DNA gyrase and topoisomerase IV, preventing bacterial replication and ultimately leading to bacterial cell death. It exhibits a broad spectrum of activity against Gram-positive and Gram-negative bacteria.
  • Cefixime 400 mg: A third-generation cephalosporin, Cefixime 400 mg functions by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. It is highly effective against both Gram-positive and Gram-negative bacteria, particularly Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria gonorrhoeae.

Indications CEFTILOX-MX Tablet, containing Moxifloxacin 400 mg & Cefixime 400 mg, is prescribed for the treatment of:

  • Respiratory Tract Infections: Pneumonia, bronchitis, sinusitis
  • Urinary Tract Infections (UTIs): Complicated and uncomplicated UTIs
  • Skin and Soft Tissue Infections
  • Sexually Transmitted Infections (STIs)
  • Gastrointestinal Infections: Typhoid fever, infectious diarrhea
  • Ear and Throat Infections: Otitis media, pharyngitis, tonsillitis

Dosage & Administration

  • The usual recommended dose is one CEFTILOX-MX Tablet (Moxifloxacin 400 mg & Cefixime 400 mg) per day or as directed by a physician.
  • To be taken orally with water, preferably after meals to minimize gastric discomfort.

Precautions & Warnings

  • Patients with a known allergy to Moxifloxacin 400 mg & Cefixime 400 mg or other quinolone/cephalosporin antibiotics should avoid this medication.
  • Should be used with caution in patients with a history of hepatic or renal impairment.
  • Avoid prolonged sun exposure, as Moxifloxacin 400 mg may increase photosensitivity.
  • Not recommended during pregnancy and lactation unless prescribed by a doctor.
  • May interact with anticoagulants, NSAIDs, and other antibiotics, requiring dose adjustments.

Side Effects Common side effects of Moxifloxacin 400 mg & Cefixime 400 mg include:

  • Nausea, vomiting, and diarrhea
  • Abdominal discomfort
  • Dizziness or headache
  • Allergic reactions like rash or itching
  • Potential tendonitis or tendon rupture (rare, but associated with fluoroquinolones like Moxifloxacin 400 mg)

Benefits of CEFTILOX-MX Tablet

  • Synergistic antibacterial action due to Moxifloxacin 400 mg & Cefixime 400 mg
  • Effective against a wide range of bacterial infections
  • Convenient once-daily dosing for better patient compliance
  • Minimal drug resistance compared to monotherapy antibiotics

Storage Instructions

  • Store at room temperature (below 30°C) in a dry place, away from direct sunlight and moisture.
  • Keep out of reach of children.

Conclusion CEFTILOX-MX Tablet, formulated with Moxifloxacin 400 mg & Cefixime 400 mg, provides an effective and reliable treatment option for various bacterial infections. Its dual-action mechanism ensures potent antibacterial efficacy, making it a preferred choice for healthcare professionals. Always use this medication under medical supervision for optimal results and minimal side effects.

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