Description

BISINTRA-CT 5/10 Tablets x Intra Life India

BISINTRA-CT 5/10 Tablets combines bisoprolol fumarate IP equivalent to bisoprolol 5 mg with cilnidipine 10 mg. The pack-confirmed presentation supplied for this page is 10×10 tablets and is marked Schedule H. It is therefore intended to be supplied and used only under a registered medical practitioner's prescription and supervision.

The two medicines act through different cardiovascular pathways. A prescriber may consider the combination when both components and strengths are suitable. It is not a universal first-line recommendation. Indian guidance allows a single-pill combination after stabilisation with the same medicines separately in the same proportion.

Pack-stated facts are separated here from class-level education. The approved Indian label and prescriber's directions control.

Product Facts

Appropriate Use and Clinical Role

BISINTRA-CT 5/10 is intended for prescription antihypertensive therapy when a clinician decides that the beta-blocker and calcium-channel-blocker components are both needed. Bisoprolol is used in the management of hypertension and is also used in some patients with angina or heart failure; however, those conditions require a clinician's diagnosis and a treatment plan, and this brand page does not extend or replace the approved Indian indication.[2] Cilnidipine is a dihydropyridine calcium-channel blocker used for hypertension.

A fixed-dose tablet may simplify a regimen after both ingredients have been assessed, but blood-pressure and pulse review remain necessary. Do not select it solely from a reading or substitute another strength without prescriber approval.

How Each Component Works

Bisoprolol. This relatively beta-1-selective adrenergic blocker can lower heart rate, cardiac workload and blood pressure. Selectivity is relative, so breathing and circulation cautions remain.

Cilnidipine. This dihydropyridine calcium-channel blocker relaxes arterial smooth muscle and lowers vascular resistance. L-type and N-type activity has been described, but this does not establish superior efficacy or tolerability. Dizziness, headache and ankle oedema remain possible.

Administration: Follow the Approved Indian Label

Take BISINTRA-CT 5/10 only as prescribed. The prescriber must decide whether this fixed strength is suitable, when it should be taken, and whether it should be continued, changed or stopped. Follow the approved Indian label and package insert for administration instructions. Swallow the tablet exactly as directed; do not split, crush or alter it unless the approved product information or prescriber specifically permits that action.

Do not start, stop, double, repeat or “make up” a dose on your own. If a dose is missed, consult the approved label or pharmacist for product-specific instructions rather than taking an extra tablet. Because abrupt beta-blocker withdrawal can worsen angina and, in some people, precipitate serious cardiac events, do not discontinue treatment suddenly without medical advice.[2] If surgery, anaesthesia, fasting, acute illness or a new medicine is planned, tell the treating clinician that you take a beta blocker.

The prescriber may review blood pressure, pulse, kidney or liver status, diabetes control and interactions. Report all medicines, eye drops, decongestants, pain medicines, supplements and alcohol.

Important Safety Information

Ask the prescriber to review the full approved label before use. Bisoprolol is contraindicated in the FDA reference label in cardiogenic shock, overt cardiac failure, second- or third-degree atrioventricular block and marked sinus bradycardia.[2] The Indian approved label may differ in wording or scope; the current Indian label controls.

Tell the prescriber about asthma, bronchospasm, a slow pulse, low blood pressure, heart block, heart failure, poor circulation, diabetes, thyroid disease, kidney or liver impairment, pregnancy, breastfeeding or prior drug reactions. Beta blockers can mask hypoglycaemia signs and affect airway tone.

Cilnidipine and other vasodilating calcium-channel blockers may cause low blood pressure, flushing, headache, dizziness or ankle swelling. Seek clinician review for new or worsening oedema, fainting, severe dizziness, chest pain, unusually slow or irregular heartbeat, worsening breathlessness or signs of an allergic reaction. Do not assume ankle swelling is harmless: it can have causes other than the medicine and needs assessment.

The combination can lower blood pressure and heart rate more than either medicine alone. Ask a pharmacist or prescriber to check other blood-pressure or heart-rate medicines, antiarrhythmics, clonidine, eye drops, diabetes medicines, sedatives and alcohol.

Common or Possible Adverse Effects

Possible effects include tiredness, weakness, dizziness, headache, low blood pressure, cold or numb hands and feet, nausea, vomiting, diarrhoea or constipation, flushing, palpitations and peripheral oedema. Bisoprolol trial data include fatigue, headache, dizziness, diarrhoea, nausea and peripheral oedema among reported adverse experiences.[2] Cilnidipine literature reports gastrointestinal symptoms, headache, dizziness, light-headedness, insomnia and, rarely, ankle oedema or rhythm-related effects.[3] Not everyone experiences these effects, and this list is not complete.

Contact a healthcare professional promptly for breathing difficulty, fainting, severe or persistent dizziness, marked slowing of the pulse, swelling of the face or throat, new chest pain, worsening heart-failure symptoms or rapidly increasing leg swelling. For a suspected serious reaction or overdose, seek urgent medical care and take the medicine pack with you.

Storage

Store BISINTRA-CT 5/10 below 25°C in a cool, dry place and protect from light, as stated on the supplied pack transcription. Keep tablets in the original packaging, away from moisture and out of children's reach. Do not use tablets after the expiry date, or if the pack is damaged or the tablets look unusual. Follow the approved Indian label for any additional storage or disposal directions.

PCD Franchise and Distributor Enquiries

Intra Life's official website presents a PCD pharma franchise model with city-wise monopoly opportunities, marketing support, product training or guidance, order support and product supply. The same site states that its network includes 46+ years of experience, 3,500+ pharma products, 2,200+ distributors, 1,000+ franchise partners and pan-India presence.[4] These are company-level website statements, not guarantees of sales, territory, margin, demand or business results.

Distributors, wholesalers, pharmacy owners, medical representatives and other eligible businesses may ask Intra Life whether BISINTRA-CT 5/10 is available for their territory, what documentation is required, and whether the product is suitable for their licensed channel. Territory rights, minimum order quantities, pricing, credit, supply timelines and promotional materials are subject to current company terms, regulatory requirements and written confirmation. No territory, margin or ranking is guaranteed on this page.

Third-Party-Manufacturing Enquiries

If you are exploring third-party manufacturing or a contract-manufacturing arrangement for an antihypertensive product, contact Intra Life to ask whether an approved, legally compliant and currently available arrangement exists for the required formulation, market and regulatory pathway. Any such enquiry would need product specifications, licences, quality documentation, manufacturing-site details, artwork and pharmacovigilance responsibilities to be assessed. This page does not promise that Intra Life offers third-party manufacturing for BISINTRA-CT 5/10, does not confirm capacity or approvals, and does not represent a quote or agreement. Use only written terms and verified regulatory documentation.

Why Partner with Intra Life

Intra Life's official website identifies Intra Life Private Limited, a pan-India PCD model, city-wise opportunities, marketing and order support, and a broad portfolio.[4] It also lists offices and the Cardivella cardiac division.[5] Confirm licences, quality documents and written terms independently; no profit, exclusivity or ranking is promised.

Frequently Asked Questions

1. What is BISINTRA-CT 5/10 Tablets?

It is a Schedule H prescription fixed-dose combination tablet containing bisoprolol fumarate IP equivalent to bisoprolol 5 mg plus cilnidipine 10 mg. The supplied pack presentation is 10×10 tablets.

2. What is the exact composition?

The exact pack-confirmed composition is bisoprolol fumarate IP equivalent to bisoprolol 5 mg + cilnidipine 10 mg. Preserve this spelling and these strengths when publishing the product.

3. What is BISINTRA-CT used for?

It is positioned as prescription antihypertensive therapy. A prescriber decides whether both components are appropriate for a particular patient; the product is not suitable for self-medication or universal first-line use.

4. Is BISINTRA-CT a first-line medicine for everyone with high blood pressure?

No. Treatment depends on the person's blood-pressure grade, medical history, pulse, other conditions and current medicines. Indian guidance describes several options and does not make this specific combination universally suitable.[1]

5. How does bisoprolol work?

Bisoprolol is a relatively beta-1-selective beta blocker that reduces sympathetic effects on the heart and can lower heart rate and cardiac workload. Selectivity is not absolute, so airway and circulation cautions remain important.[2]

6. How does cilnidipine work?

Cilnidipine is a dihydropyridine calcium-channel blocker that relaxes arterial smooth muscle and lowers vascular resistance. Educational sources describe L-type and N-type calcium-channel activity.[3]

7. How should I take it?

Follow the approved Indian label, package insert and prescriber's directions. Do not change the dose, take an extra tablet or stop suddenly. This page does not give individual dosing instructions.

8. Can I stop BISINTRA-CT when my blood pressure improves?

No. Do not stop a beta blocker abruptly or without medical advice. A prescriber may decide whether and how to taper or change treatment.[2]

9. Who should discuss this medicine carefully with a clinician?

People with a slow pulse, heart block, low blood pressure, heart failure, asthma or bronchospasm, diabetes, peripheral circulation problems, kidney or liver impairment, thyroid disease, pregnancy or breastfeeding should disclose these facts before treatment.

10. What side effects can occur?

Possible effects include fatigue, dizziness, headache, low blood pressure, cold extremities, nausea, bowel changes, flushing, palpitations and ankle or peripheral oedema. Seek urgent help for breathing difficulty, fainting, severe chest symptoms or facial/throat swelling.

11. What is the pack size and storage condition?

The supplied pack facts state 10×10 tablets and storage below 25°C in a cool, dry place, protected from light.

12. What is the price of BISINTRA-CT?

Price, availability, batch details and applicable taxes can change. Request the current quotation from Intra Life or an authorised channel; this page does not publish an unverified price.

13. Can I enquire about BISINTRA-CT wholesale supply?

Yes. A licensed distributor, wholesaler or pharmacy may contact Intra Life with the territory, required quantity and business details. Supply is subject to current terms, documentation, stock and applicable law.

14. Is a PCD franchise available for this product?

Ask Intra Life about current territory availability and written terms. The company website describes city-wise PCD opportunities, but no specific BISINTRA-CT territory, monopoly right, margin or business outcome is guaranteed here.[4]

15. Does Intra Life offer third-party manufacturing for BISINTRA-CT?

Ask the company directly. A compliant arrangement, if available, would require technical, regulatory, quality and commercial due diligence. This page does not confirm service availability, approvals, capacity or pricing.

Medical and B2B Disclaimer

Medical disclaimer: This page is general educational and product information for website publication. It is not a diagnosis, prescription, treatment recommendation or substitute for the approved Indian label, package insert, registered medical practitioner or pharmacist. BISINTRA-CT 5/10 is a Schedule H prescription drug. Do not self-medicate, share tablets, alter treatment or use this copy to make an individual dosing decision. Product information, indications, contraindications, warnings and availability must be checked against the current approved Indian label and pack before publication and supply.

B2B disclaimer: PCD, distribution, wholesale and third-party-manufacturing enquiries are subject to eligibility, territory, stock, licences, quality documentation, regulatory approval, written commercial terms and Intra Life's current policies. No cure, superior efficacy, guaranteed absence of side effects, guaranteed franchise territory, guaranteed profit, guaranteed supply or guaranteed search ranking is promised.

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